A Pilot Trial Assessing the Feasibility and Efficacy of a Novel Powder for Rapid Wound Healing

It is well-understood that wound care poses a significant burden on the healthcare system and patient well-being. As such, it imperative to develop efficient methods facilitate tissue repair. Our group previously developed nutritional gel scaffold, proven accelerate Due its gel-like properties, this scaffold requires time-consuming reconstitution, optimized for cavernous wounds. This pilot study examined feasibility of powdered form healing full-thickness wounds, thus broadening range applications, while providing practical product. Splinted wounds were generated backs 6 mice, treated with either powder, original or no treatment. Feasibility efficacy powder was assessed through comparison clinical measurements histological assessments. There effect treatment rate epithelialization [H(3) = 8.346, p 0.0024] days epithelial closure 8.482, 0.0061]. Post hoc analysis revealed requiring reconstitution simple apply, sufficient compared untreated (p < 0.05). Furthermore, our results suggest application did not alter certain processes associated progress, such as epidermal thickness collagen deposition. may provide novel alternative by accelerating epithelialization, Future studies necessitate further evaluation measures larger sample size.